Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM387058'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM387058 (1-(4-Methoxyphenyl)-7-oxo-6-(1-(3-oxomorpholino)pi...) Show SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C3CCN(CC3)N3CCOCC3=O)C(=O)c12 Show InChI InChI=1S/C23H28N6O5/c1-33-17-4-2-16(3-5-17)29-21-18(20(25-29)22(24)31)8-11-27(23(21)32)15-6-9-26(10-7-15)28-12-13-34-14-19(28)30/h2-5,15H,6-14H2,1H3,(H2,24,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Thrombin: In the assay for measuring the inhibition of human thrombin activity buffer (10 mM HEPES buffer, pH 7.4, 2 mM CaCl2) is used. The IC50 is m...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2F1921P
					More data for this Ligand-Target Pair