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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50066767'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50066767
PNG
((3R,6R,8aS)-6-Amino-5-oxo-hexahydro-thiazolo[3,2-a...)
Show SMILES N[C@@H]1CC[C@@H]2SC[C@H](N2C1=O)C(=O)NCCCCNC(N)=N
Show InChI InChI=1S/C13H24N6O2S/c14-8-3-4-10-19(12(8)21)9(7-22-10)11(20)17-5-1-2-6-18-13(15)16/h8-10H,1-7,14H2,(H,17,20)(H4,15,16,18)/t8-,9+,10+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 6.24E+4n/an/an/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Invitro inhibition was measured against Human Thrombin.

J Med Chem 41: 3664-74 (1998)


Article DOI: 10.1021/jm981013e
BindingDB Entry DOI: 10.7270/Q22R3QSZ
More data for this
Ligand-Target Pair