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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070683'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070683
PNG
(CHEMBL2372728 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc(O)ccc1O)[C@@H](C)O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C26H38N4O9/c1-5-13(3)20(24(36)27-17(6-2)26(38)39)28-23(35)18-8-7-11-30(18)25(37)21(14(4)31)29-22(34)16-12-15(32)9-10-19(16)33/h9-10,12-14,17-18,20-21,31-33H,5-8,11H2,1-4H3,(H,27,36)(H,28,35)(H,29,34)(H,38,39)/t13?,14?,17?,18-,20-,21-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 3.15E+6n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair