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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070698'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070698
PNG
(CHEMBL2372670 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](CC(C)C)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C28H42N4O8/c1-6-16(5)23(26(37)29-19(7-2)28(39)40)31-25(36)21-9-8-12-32(21)27(38)20(13-15(3)4)30-24(35)18-14-17(33)10-11-22(18)34/h10-11,14-16,19-21,23,33-34H,6-9,12-13H2,1-5H3,(H,29,37)(H,30,35)(H,31,36)(H,39,40)/t16?,19?,20-,21-,23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.78E+6n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair