Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070716'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50070716 (CHEMBL2372747 | Nazumamide A (NAZA) analogue) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC)C(O)=O Show InChI InChI=1S/C29H48N6O8/c1-4-17(3)24(28(41)32-20(5-2)29(42)43)35-27(40)22(11-7-9-15-31)34-26(39)21(10-6-8-14-30)33-25(38)19-16-18(36)12-13-23(19)37/h12-13,16-17,20-22,24,36-37H,4-11,14-15,30-31H2,1-3H3,(H,32,41)(H,33,38)(H,34,39)(H,35,40)(H,42,43)/t17?,20?,21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.83E+5	n/a	n/a	n/a	n/a	8.3	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.				Bioorg Med Chem Lett 8: 1669-72 (1999) BindingDB Entry DOI: 10.7270/Q2G73CV8
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50070716 (CHEMBL2372747 | Nazumamide A (NAZA) analogue) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC)C(O)=O Show InChI InChI=1S/C29H48N6O8/c1-4-17(3)24(28(41)32-20(5-2)29(42)43)35-27(40)22(11-7-9-15-31)34-26(39)21(10-6-8-14-30)33-25(38)19-16-18(36)12-13-23(19)37/h12-13,16-17,20-22,24,36-37H,4-11,14-15,30-31H2,1-3H3,(H,32,41)(H,33,38)(H,34,39)(H,35,40)(H,42,43)/t17?,20?,21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.08E+5	n/a	n/a	n/a	n/a	8.3	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.				Bioorg Med Chem Lett 8: 1669-72 (1999) BindingDB Entry DOI: 10.7270/Q2G73CV8
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50070716 (CHEMBL2372747 | Nazumamide A (NAZA) analogue) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC)C(O)=O Show InChI InChI=1S/C29H48N6O8/c1-4-17(3)24(28(41)32-20(5-2)29(42)43)35-27(40)22(11-7-9-15-31)34-26(39)21(10-6-8-14-30)33-25(38)19-16-18(36)12-13-23(19)37/h12-13,16-17,20-22,24,36-37H,4-11,14-15,30-31H2,1-3H3,(H,32,41)(H,33,38)(H,34,39)(H,35,40)(H,42,43)/t17?,20?,21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.08E+5	n/a	n/a	n/a	n/a	8.3	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.				Bioorg Med Chem Lett 8: 1669-72 (1999) BindingDB Entry DOI: 10.7270/Q2G73CV8
					More data for this Ligand-Target Pair