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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070720'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070720
PNG
(CHEMBL2372704 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C28H43N5O10/c1-4-15(3)23(27(41)32-20(10-12-22(36)37)25(39)30-18(5-2)28(42)43)33-26(40)19(8-6-7-13-29)31-24(38)17-14-16(34)9-11-21(17)35/h9,11,14-15,18-20,23,34-35H,4-8,10,12-13,29H2,1-3H3,(H,30,39)(H,31,38)(H,32,41)(H,33,40)(H,36,37)(H,42,43)/t15?,18?,19-,20-,23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 4.58E+5n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair