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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070741'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070741
PNG
(CHEMBL2372672 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C29H47N5O8/c1-6-17(5)24(28(40)31-20(7-2)29(41)42)34-27(39)22(14-16(3)4)33-26(38)21(10-8-9-13-30)32-25(37)19-15-18(35)11-12-23(19)36/h11-12,15-17,20-22,24,35-36H,6-10,13-14,30H2,1-5H3,(H,31,40)(H,32,37)(H,33,38)(H,34,39)(H,41,42)/t17?,20?,21-,22+,24-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.37E+5n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair