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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50070760'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50070760
PNG
(CHEMBL2372660 | Nazumamide A (NAZA) analogue)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc(O)ccc1O)C(=O)N[C@@H](CC)C(O)=O
Show InChI InChI=1S/C31H40N4O9/c1-4-17(3)26(29(41)32-22(5-2)31(43)44)34-28(40)24-7-6-14-35(24)30(42)23(15-18-8-10-19(36)11-9-18)33-27(39)21-16-20(37)12-13-25(21)38/h8-13,16-17,22-24,26,36-38H,4-7,14-15H2,1-3H3,(H,32,41)(H,33,39)(H,34,40)(H,43,44)/t17?,22?,23-,24-,26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 2.43E+6n/an/an/an/a8.3n/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Anti-thrombin activity by competitive enzyme assay using the fluorogenic substrate Tos-Gly-Pro-Arg-AMC at pH 8.3.

Bioorg Med Chem Lett 8: 1669-72 (1999)


BindingDB Entry DOI: 10.7270/Q2G73CV8
More data for this
Ligand-Target Pair