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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50093144'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50093144
PNG
(CHEMBL46120 | N-(4-Guanidino-benzyl)-N'-(4-{[2-(4-...)
Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6]-c2ccc(-[#6]-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7]-[#6]-c3ccc(cc3)\[#7]=[#6](\[#7])-[#7])cc2)cc1
Show InChI InChI=1S/C30H36N10O4/c31-29(32)39-23-9-5-21(6-10-23)17-37-27(43)13-25(41)35-15-19-1-2-20(4-3-19)16-36-26(42)14-28(44)38-18-22-7-11-24(12-8-22)40-30(33)34/h1-12H,13-18H2,(H,35,41)(H,36,42)(H,37,43)(H,38,44)(H4,31,32,39)(H4,33,34,40)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



Axys Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory potency against thrombin

Bioorg Med Chem Lett 10: 2357-60 (2001)


BindingDB Entry DOI: 10.7270/Q2NP23NX
More data for this
Ligand-Target Pair