Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50146534'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50146534 (CHEMBL100732 | [4-(6-Chloro-naphthalene-2-sulfonyl...) Show SMILES CN1CCc2nc(sc2C1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C22H23ClN4O3S2/c1-25-7-6-19-20(14-25)31-21(24-19)22(28)26-8-10-27(11-9-26)32(29,30)18-5-3-15-12-17(23)4-2-16(15)13-18/h2-5,12-13H,6-11,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against human thrombin				Bioorg Med Chem Lett 14: 2935-9 (2004) Article DOI: 10.1016/j.bmcl.2004.03.036 BindingDB Entry DOI: 10.7270/Q2VH5N9B
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50146534 (CHEMBL100732 | [4-(6-Chloro-naphthalene-2-sulfonyl...) Show SMILES CN1CCc2nc(sc2C1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C22H23ClN4O3S2/c1-25-7-6-19-20(14-25)31-21(24-19)22(28)26-8-10-27(11-9-26)32(29,30)18-5-3-15-12-17(23)4-2-16(15)13-18/h2-5,12-13H,6-11,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Concentration required to inhibit thrombin activity by 50%				J Med Chem 47: 5167-82 (2004) Article DOI: 10.1021/jm049884d BindingDB Entry DOI: 10.7270/Q2V987JK
					More data for this Ligand-Target Pair