Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50195761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50195761 (CHEMBL437353 | N-[(S)-4-guanidino-1-(piperidine-1-...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]S(=O)(=O)c1cccc(c1)C(F)(F)F)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C18H26F3N5O3S/c19-18(20,21)13-6-4-7-14(12-13)30(28,29)25-15(8-5-9-24-17(22)23)16(27)26-10-2-1-3-11-26/h4,6-7,12,15,25H,1-3,5,8-11H2,(H4,22,23,24)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université catholique de Louvain Curated by ChEMBL					Assay Description Inhibition of human alpha thrombin				Eur J Med Chem 42: 37-53 (2007) Article DOI: 10.1016/j.ejmech.2006.07.010 BindingDB Entry DOI: 10.7270/Q29886N6
					More data for this Ligand-Target Pair