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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50215304'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50215304
PNG
(CHEMBL98212)
Show SMILES Cc1cnc(NCC2(CC2)c2ccc(F)cc2)c(=O)n1CC(=O)NCc1ccc2[nH]nc(N)c2c1
Show InChI InChI=1S/C25H26FN7O2/c1-15-11-29-23(30-14-25(8-9-25)17-3-5-18(26)6-4-17)24(35)33(15)13-21(34)28-12-16-2-7-20-19(10-16)22(27)32-31-20/h2-7,10-11H,8-9,12-14H2,1H3,(H,28,34)(H,29,30)(H3,27,31,32)
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 15n/an/an/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate

Bioorg Med Chem Lett 12: 2925-30 (2002)


BindingDB Entry DOI: 10.7270/Q27946WJ
More data for this
Ligand-Target Pair