Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-3' and Ligand = 'BDBM50294831'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-3 (Homo sapiens (Human))	BDBM50294831 (4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES O=C(Nc1cccc2cccnc12)[C@H]1CC[C@H](CN2C(=O)[C@H]3[C@@H]4C[C@@H](C=C4)[C@H]3C2=O)CC1 |r,wU:22.24,24.25,13.14,wD:16.18,21.22,27.31,c:27,(26.78,-20.85,;25.44,-21.6,;25.42,-23.14,;26.74,-23.93,;28.09,-23.18,;29.42,-23.97,;29.4,-25.51,;28.06,-26.27,;28.04,-27.8,;26.7,-28.56,;25.37,-27.78,;25.39,-26.23,;26.73,-25.48,;24.11,-20.82,;22.78,-21.57,;21.45,-20.79,;21.47,-19.24,;20.15,-18.45,;18.61,-18.45,;17.71,-17.22,;18.18,-15.75,;16.24,-17.69,;14.92,-16.92,;15.3,-18.41,;14.89,-19.89,;13.58,-19.22,;13.58,-17.68,;16.24,-19.23,;17.7,-19.71,;18.18,-21.18,;22.82,-18.49,;24.14,-19.28,)| Show InChI InChI=1S/C26H27N3O3/c30-24(28-20-5-1-3-16-4-2-12-27-23(16)20)17-8-6-15(7-9-17)14-29-25(31)21-18-10-11-19(13-18)22(21)26(29)32/h1-5,10-12,15,17-19,21-22H,6-9,13-14H2,(H,28,30)/t15-,17-,18-,19+,21-,22+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center at Dallas Curated by ChEMBL					Assay Description Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay				Bioorg Med Chem Lett 19: 3825-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.040 BindingDB Entry DOI: 10.7270/Q2DZ08BS
					More data for this Ligand-Target Pair