Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase LCK' and Ligand = 'BDBM26160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26160 (2,4-dianilino pyrimidine, 17 | 3-({4-[(5-methanesu...) Show SMILES Cc1ccc(NS(C)(=O)=O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C19H20N6O3S/c1-12-6-7-15(25-29(2,27)28)11-16(12)23-17-8-9-21-19(24-17)22-14-5-3-4-13(10-14)18(20)26/h3-11,25H,1-2H3,(H2,20,26)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
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