Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase LCK' and Ligand = 'BDBM26178'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26178 (2,4-dianilino pyrimidine, 35 | 3-({4-[(2-methyl-1H...) Show SMILES Cc1nc2cccc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)c2[nH]1 Show InChI InChI=1S/C19H17N7O/c1-11-22-14-6-3-7-15(17(14)23-11)25-16-8-9-21-19(26-16)24-13-5-2-4-12(10-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,23)(H2,21,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
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