Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase LCK' and Ligand = 'BDBM26181'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26181 (2,4-dianilino pyrimidine, 38 | 3-({4-[(6-methyl-1H...) Show SMILES Cc1cc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c2cn[nH]c2c1 Show InChI InChI=1S/C19H17N7O/c1-11-7-15(14-10-22-26-16(14)8-11)24-17-5-6-21-19(25-17)23-13-4-2-3-12(9-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,26)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
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