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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205299'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM205299
PNG
(US9249125, 52)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)c3)c3ccccc23)n(n1)-c1cccc(OCCN2CCOCC2)c1
Show InChI InChI=1S/C42H43N9O4/c1-42(2,3)38-26-40(51(49-38)30-7-6-8-31(24-30)54-22-19-50-17-20-53-21-18-50)47-41(52)46-36-13-14-37(34-10-5-4-9-33(34)36)55-32-15-16-43-39(25-32)45-29-11-12-35-28(23-29)27-44-48-35/h4-16,23-27H,17-22H2,1-3H3,(H,43,45)(H,44,48)(H2,46,47,52)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
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US Patent
n/an/a 3n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair