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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205343'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM205343
PNG
(US9249125, 14)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(Nc4ccc5[nH]ncc5c4)ncn3)c3ccccc23)n(n1)-c1ccc(=O)n(CCO)c1
Show InChI InChI=1S/C36H34N10O4/c1-36(2,3)30-17-32(46(44-30)24-9-13-34(48)45(20-24)14-15-47)42-35(49)41-28-11-12-29(26-7-5-4-6-25(26)28)50-33-18-31(37-21-38-33)40-23-8-10-27-22(16-23)19-39-43-27/h4-13,16-21,47H,14-15H2,1-3H3,(H,39,43)(H,37,38,40)(H2,41,42,49)
PDB
MMDB

KEGG

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PC cid
PC sid
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US Patent
n/an/a 2n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair