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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM347674'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM347674
PNG
(3-Ethynyl-5-((4-((4-(3-(3-(2-methylbut-3-yn-2-yl)-...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(cc(c3)C(=O)NCCN3CCOCC3)C#C)n2)c2ccccc12)C(C)(C)C#C
Show InChI InChI=1S/C45H43N9O4/c1-6-31-26-32(42(55)46-20-21-53-22-24-57-25-23-53)28-33(27-31)48-43-47-19-18-41(51-43)58-38-17-16-37(35-10-8-9-11-36(35)38)49-44(56)50-40-29-39(45(4,5)7-2)52-54(40)34-14-12-30(3)13-15-34/h1-2,8-19,26-29H,20-25H2,3-5H3,(H,46,55)(H,47,48,51)(H2,49,50,56)
PDB
MMDB

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US Patent
n/an/a 16n/an/an/an/an/an/a



Respivert Limited; Topivert Pharma Limited

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9790209 (2017)


BindingDB Entry DOI: 10.7270/Q2TQ63PS
More data for this
Ligand-Target Pair