Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM381080'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM381080 (US9890185, Example 38(c)) Show SMILES COc1cc(CO)cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(c4OC)P(C)(C)=O)C(C)(C)C)c4ccccc34)ccn2)c1 Show InChI InChI=1S/C37H41N4O6P/c1-37(2,3)24-18-31(35(46-5)33(19-24)48(6,7)44)41-36(43)40-30-12-13-32(29-11-9-8-10-28(29)30)47-26-14-15-38-34(21-26)39-25-16-23(22-42)17-27(20-25)45-4/h8-21,42H,22H2,1-7H3,(H,38,39)(H2,40,41,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon					Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...				J Med Chem 51: 5680-9 (2008) BindingDB Entry DOI: 10.7270/Q2FB558N
					More data for this Ligand-Target Pair