Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM4114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4114 (4-bromo-9-[(4-tert-butylphenyl)carbonyl]-9H-carbaz...) Show SMILES CC(C)(C)c1ccc(cc1)C(=O)n1c2cc(O)c(O)cc2c2c(Br)cc(O)c(O)c12 Show InChI InChI=1S/C23H20BrNO5/c1-23(2,3)12-6-4-11(5-7-12)22(30)25-15-10-17(27)16(26)8-13(15)19-14(24)9-18(28)21(29)20(19)25/h4-10,26-29H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of pp60c-src activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
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