Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50221566 (4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TargeGen, Inc. Curated by ChEMBL | Assay Description Inhibition of Src | Bioorg Med Chem Lett 17: 5812-8 (2007) Article DOI: 10.1016/j.bmcl.2007.08.043 BindingDB Entry DOI: 10.7270/Q2M32VGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50221566 (4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | 25 |
TargeGen, Inc. US Patent | Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp. | US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50221566 (4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TargeGen Inc. Curated by ChEMBL | Assay Description Inhibition of Src | J Med Chem 51: 1546-59 (2008) Article DOI: 10.1021/jm7011276 BindingDB Entry DOI: 10.7270/Q2NV9K3X | |||||||||||
More data for this Ligand-Target Pair |