BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50252978'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50252978 ((2'Z-3'E)-6-Bromoindirubin-3'-[O-(2-pyrrolidin-1-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Beckman Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATP				J Nat Prod 79: 2464-2471 (2016) Article DOI: 10.1021/acs.jnatprod.6b00285 BindingDB Entry DOI: 10.7270/Q2GF0WZR
Beckman Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50252978 ((2'Z-3'E)-6-Bromoindirubin-3'-[O-(2-pyrrolidin-1-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Beckman Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATP				J Nat Prod 79: 2464-2471 (2016) Article DOI: 10.1021/acs.jnatprod.6b00285 BindingDB Entry DOI: 10.7270/Q2GF0WZR
Beckman Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair