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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50437151'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Gallus gallus (Chicken))		BDBM50437151
PNG
(CHEMBL2403817)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4ccc(N)cc34)cc2)n(n1)-c1cccc(NC(=O)OCC2c3ccccc3-c3ccccc23)c1
Show InChI InChI=1S/C43H39N9O3/c1-43(2,3)38-23-39(50-41(53)48-28-18-16-27(17-19-28)47-40-35-21-26(44)15-20-37(35)45-25-46-40)52(51-38)30-10-8-9-29(22-30)49-42(54)55-24-36-33-13-6-4-11-31(33)32-12-5-7-14-34(32)36/h4-23,25,36H,24,44H2,1-3H3,(H,49,54)(H,45,46,47)(H2,48,50,53)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 145n/an/an/an/an/an/a



Technical University of Dortmund

Curated by ChEMBL


Assay Description
Inhibition of chicken wild-type cSRC (251 to 533)-mediated phosphorylation of biotinylated poly-Glu-Tyr expressed in Escherichia coli BL21(DE3) prein...

J Med Chem 56: 5757-72 (2014)


Article DOI: 10.1021/jm4004076
BindingDB Entry DOI: 10.7270/Q2W37XPH
More data for this
Ligand-Target Pair