Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src [251-533,T338C]' and Ligand = 'BDBM234851'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken))	BDBM234851 (US9353116, 8) Show SMILES CC(C)n1nc(Cc2ccc(NC(=O)C=C)cc2)c2c(N)ncnc12 Show InChI InChI=1S/C18H20N6O/c1-4-15(25)22-13-7-5-12(6-8-13)9-14-16-17(19)20-10-21-18(16)24(23-14)11(2)3/h4-8,10-11H,1,9H2,2-3H3,(H,22,25)(H2,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
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