Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src [251-533]' and Ligand = 'BDBM234847'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src [251-533] (Gallus gallus (Chicken))	BDBM234847 (US9353116, 4) Show SMILES CC(C)n1nc(-c2cccc(NS(=O)(=O)C=C)c2)c2cncnc12 Show InChI InChI=1S/C16H17N5O2S/c1-4-24(22,23)20-13-7-5-6-12(8-13)15-14-9-17-10-18-16(14)21(19-15)11(2)3/h4-11,20H,1H2,2-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
The Regents of the University of California US Patent					Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat...				US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7
					More data for this Ligand-Target Pair