Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM488431'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM488431 (1-(2-(4-Amino-1-(tert-butyl)-1H-pyrazolo[3,4- d]py...) Show SMILES CNC(=O)Nc1ccc2cc([nH]c2c1)-c1nn(c2ncnc(N)c12)C(C)(C)C Show InChI InChI=1S/C19H22N8O/c1-19(2,3)27-17-14(16(20)22-9-23-17)15(26-27)13-7-10-5-6-11(8-12(10)25-13)24-18(28)21-4/h5-9,25H,1-4H3,(H2,20,22,23)(H2,21,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description RET, RETV804M and KDR: Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q21Z4880
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM488431 (1-(2-(4-Amino-1-(tert-butyl)-1H-pyrazolo[3,4- d]py...) Show SMILES CNC(=O)Nc1ccc2cc([nH]c2c1)-c1nn(c2ncnc(N)c12)C(C)(C)C Show InChI InChI=1S/C19H22N8O/c1-19(2,3)27-17-14(16(20)22-9-23-17)15(26-27)13-7-10-5-6-11(8-12(10)25-13)24-18(28)21-4/h5-9,25H,1-4H3,(H2,20,22,23)(H2,21,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description Kinase activity was detected using CisBio HTRF kinEASE kit based on time-resolved fluorescence transfer (FRET). The assay was performed in 384-well w...				US Patent US10954241 (2021) BindingDB Entry DOI: 10.7270/Q2WQ06XH
					More data for this Ligand-Target Pair