Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50027460'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50027460 (CHEMBL3329401) Show SMILES Clc1cccc(NC(=O)Cc2cccc(Oc3ccc4nccn4n3)c2)c1 Show InChI InChI=1S/C20H15ClN4O2/c21-15-4-2-5-16(13-15)23-19(26)12-14-3-1-6-17(11-14)27-20-8-7-18-22-9-10-25(18)24-20/h1-11,13H,12H2,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of RET (unknown origin) pre-incubated for 60 mins before substrate addition in presence of 9 uM ATP by microfluidic assay				Eur J Med Chem 86: 714-23 (2014) Article DOI: 10.1016/j.ejmech.2014.09.023 BindingDB Entry DOI: 10.7270/Q2TD9ZZR
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