Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50134788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50134788 (CHEMBL3752736) Show SMILES CC(C)n1nc(C2=NOC(C2)c2ccccc2)c2c(N)ncnc12 |t:6| Show InChI InChI=1S/C17H18N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h3-7,9-10,13H,8H2,1-2H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP				J Med Chem 59: 358-73 (2016) Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50134788 (CHEMBL3752736) Show SMILES CC(C)n1nc(C2=NOC(C2)c2ccccc2)c2c(N)ncnc12 |t:6| Show InChI InChI=1S/C17H18N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h3-7,9-10,13H,8H2,1-2H3,(H2,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP				J Med Chem 59: 358-73 (2016) Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M
					More data for this Ligand-Target Pair