Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50214120'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50214120 (4-(3-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidaz...) Show SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ncc(cc12)-c1cncc2ccccc12 Show InChI InChI=1S/C27H24N8/c1-34-8-10-35(11-9-34)19-6-7-23-24(13-19)31-27(30-23)25-21-12-18(15-29-26(21)33-32-25)22-16-28-14-17-4-2-3-5-20(17)22/h2-7,12-16H,8-11H2,1H3,(H,30,31)(H,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Tsing Hua University Curated by ChEMBL					Assay Description Inhibition of RET kinase				Bioorg Med Chem Lett 21: 4490-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.003 BindingDB Entry DOI: 10.7270/Q2BV7H06
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50214120 (4-(3-(5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidaz...) Show SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ncc(cc12)-c1cncc2ccccc12 Show InChI InChI=1S/C27H24N8/c1-34-8-10-35(11-9-34)19-6-7-23-24(13-19)31-27(30-23)25-21-12-18(15-29-26(21)33-32-25)22-16-28-14-17-4-2-3-5-20(17)22/h2-7,12-16H,8-11H2,1H3,(H,30,31)(H,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibition of RET				Bioorg Med Chem Lett 17: 4297-302 (2007) Article DOI: 10.1016/j.bmcl.2007.05.029 BindingDB Entry DOI: 10.7270/Q20C4VGJ
					More data for this Ligand-Target Pair