Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret [G810R]' and Ligand = 'BDBM597673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret [G810R] (Homo sapiens (Human))	BDBM597673 (US11603374, Example 28) Show SMILES Nc1ncnc2n(cc(-c3cc(on3)C3CC3)c12)[C@@H]1C[C@H](CO)C1 |r,wU:18.21,20.24,(-2.78,4.69,;-3.17,3.2,;-4.68,2.88,;-5.16,1.42,;-4.13,.27,;-2.62,.59,;-1.37,-.31,;-.13,.59,;-.6,2.06,;.17,3.39,;1.71,3.39,;2.18,4.85,;.94,5.76,;-.31,4.85,;3.67,5.25,;5.16,4.85,;4.76,6.34,;-2.14,2.06,;-1.37,-1.85,;-2.46,-2.94,;-1.37,-4.03,;-1.37,-5.57,;-.04,-6.34,;-.29,-2.94,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z323KZ
					More data for this Ligand-Target Pair