Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50046226'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50046226 (2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...) Show SMILES Nc1nc2N(Cc3cccs3)CNc2c(=O)[nH]1 Show InChI InChI=1S/C10H11N5OS/c11-10-13-8-7(9(16)14-10)12-5-15(8)4-6-2-1-3-17-6/h1-3,12H,4-5H2,(H3,11,13,14,16)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphate				J Med Chem 36: 55-69 (1993) BindingDB Entry DOI: 10.7270/Q2B27TCX
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50046226 (2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...) Show SMILES Nc1nc2N(Cc3cccs3)CNc2c(=O)[nH]1 Show InChI InChI=1S/C10H11N5OS/c11-10-13-8-7(9(16)14-10)12-5-15(8)4-6-2-1-3-17-6/h1-3,12H,4-5H2,(H3,11,13,14,16)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphate				J Med Chem 36: 55-69 (1993) BindingDB Entry DOI: 10.7270/Q2B27TCX
					More data for this Ligand-Target Pair