Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50078457'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50078457 (2-Amino-7-biphenyl-4-ylmethyl-3,5-dihydro-pyrrolo[...) Show SMILES Nc1nc2c(Cc3ccc(cc3)-c3ccccc3)c[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C19H16N4O/c20-19-22-16-15(11-21-17(16)18(24)23-19)10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9,11,21H,10H2,(H3,20,22,23,24)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	546	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.				J Med Chem 42: 2422-31 (1999) Article DOI: 10.1021/jm990037y BindingDB Entry DOI: 10.7270/Q2CR5SKN
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