Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Pyruvate kinase PKM' and Ligand = 'BDBM50361489'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase PKM (Homo sapiens (Human))	BDBM50361489 (CHEMBL1939114) Show SMILES C[C@@H](CO)Nc1cc2NC(=O)CCc2cc1S(=O)(=O)Nc1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C19H22FN3O4S/c1-11-7-14(4-5-15(11)20)23-28(26,27)18-8-13-3-6-19(25)22-16(13)9-17(18)21-12(2)10-24/h4-5,7-9,12,21,23-24H,3,6,10H2,1-2H3,(H,22,25)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay				Bioorg Med Chem Lett 21: 6322-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.114 BindingDB Entry DOI: 10.7270/Q28C9WQG
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