Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM108443'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM108443 (US8609688, 21) Show SMILES Nc1ncccc1-c1nc2ccc(Sc3ccccc3)nc2n1-c1ccc(cc1)C1(N)CCC1 Show InChI InChI=1S/C27H24N6S/c28-24-21(8-4-17-30-24)25-31-22-13-14-23(34-20-6-2-1-3-7-20)32-26(22)33(25)19-11-9-18(10-12-19)27(29)15-5-16-27/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
ArQule, Inc. US Patent					Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...				US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM108443 (US8609688, 21) Show SMILES Nc1ncccc1-c1nc2ccc(Sc3ccccc3)nc2n1-c1ccc(cc1)C1(N)CCC1 Show InChI InChI=1S/C27H24N6S/c28-24-21(8-4-17-30-24)25-31-22-13-14-23(34-20-6-2-1-3-7-20)32-26(22)33(25)19-11-9-18(10-12-19)27(29)15-5-16-27/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	110	n/a	n/a	n/a	7.5	80
ArQule, Inc. US Patent					Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...				US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M
					More data for this Ligand-Target Pair