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Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM218247'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM218247
PNG
(US9260435, 5)
Show SMILES CCOC(=O)c1cn2c(c(nc2cn1)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1
Show InChI InChI=1S/C25H24N4O2/c1-2-31-24(30)20-16-29-21(15-27-20)28-22(23(29)18-7-4-3-5-8-18)17-9-11-19(12-10-17)25(26)13-6-14-25/h3-5,7-12,15-16H,2,6,13-14,26H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 100n/an/an/an/a7.522



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
His-tagged human recombinant kinase full-length Akt1 expressed in insect cells was purchased form Invitrogen (part number PV 3599). As substrate for ...

US Patent US9260435 (2016)


BindingDB Entry DOI: 10.7270/Q2K936CJ
More data for this
Ligand-Target Pair