Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM24860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM24860 (({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrim...) Show SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CNCCc2nccs2)cc1 Show InChI InChI=1S/C26H23N5S2/c1-32-26-29-17-21-15-22(19-5-3-2-4-6-19)24(30-25(21)31-26)20-9-7-18(8-10-20)16-27-12-11-23-28-13-14-33-23/h2-10,13-15,17,27H,11-12,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	7.5	22
Merck Research Laboratories					Assay Description Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...				Bioorg Med Chem Lett 18: 1274-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.054 BindingDB Entry DOI: 10.7270/Q2G73C02
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