Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM24888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM24888 (2,3,5-trisubstituted pyridine, 10d | 5-{5-phenyl-6...) Show SMILES Nc1nnc(s1)-c1cnc(-c2ccc(CN3CCC(CC3)n3cc(cn3)-c3ccccn3)cc2)c(c1)-c1ccccc1 Show InChI InChI=1S/C33H30N8S/c34-33-39-38-32(42-33)26-18-29(24-6-2-1-3-7-24)31(36-19-26)25-11-9-23(10-12-25)21-40-16-13-28(14-17-40)41-22-27(20-37-41)30-8-4-5-15-35-30/h1-12,15,18-20,22,28H,13-14,16-17,21H2,(H2,34,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	7.5	22
Merck Research Laboratories					Assay Description Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...				Bioorg Med Chem Lett 18: 2194-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.040 BindingDB Entry DOI: 10.7270/Q2BG2M8B
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