Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM369723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369723 (US10233160, Compound 13 | US9981925, Compound 13) Show SMILES CN(C)C[C@@H](Nc1nnnc2c(cccc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18ClF3N6O/c1-29(2)9-15(10-6-7-14(20)13(8-10)19(21,22)23)25-18-12-5-3-4-11(17(24)30)16(12)26-28-27-18/h3-8,15H,9H2,1-2H3,(H2,24,30)(H,25,26,27)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				Bioorg Med Chem Lett 18: 4181-5 (2008) BindingDB Entry DOI: 10.7270/Q2319Z6K
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369723 (US10233160, Compound 13 | US9981925, Compound 13) Show SMILES CN(C)C[C@@H](Nc1nnnc2c(cccc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18ClF3N6O/c1-29(2)9-15(10-6-7-14(20)13(8-10)19(21,22)23)25-18-12-5-3-4-11(17(24)30)16(12)26-28-27-18/h3-8,15H,9H2,1-2H3,(H2,24,30)(H,25,26,27)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair