Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM369746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369746 (US10233160, Compound 37 | US9981925, Compound 37) Show SMILES CC(C)c1ccc(cc1)[C@@H](CN1CCC1)Nc1ncnc2c(ccnc12)C(N)=O |r| Show InChI InChI=1S/C22H26N6O/c1-14(2)15-4-6-16(7-5-15)18(12-28-10-3-11-28)27-22-20-19(25-13-26-22)17(21(23)29)8-9-24-20/h4-9,13-14,18H,3,10-12H2,1-2H3,(H2,23,29)(H,25,26,27)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				Bioorg Med Chem Lett 18: 4181-5 (2008) BindingDB Entry DOI: 10.7270/Q2319Z6K
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369746 (US10233160, Compound 37 | US9981925, Compound 37) Show SMILES CC(C)c1ccc(cc1)[C@@H](CN1CCC1)Nc1ncnc2c(ccnc12)C(N)=O |r| Show InChI InChI=1S/C22H26N6O/c1-14(2)15-4-6-16(7-5-15)18(12-28-10-3-11-28)27-22-20-19(25-13-26-22)17(21(23)29)8-9-24-20/h4-9,13-14,18H,3,10-12H2,1-2H3,(H2,23,29)(H,25,26,27)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair