Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM369753'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369753 (US10233160, Compound 44 | US9981925, Compound 44) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(C)c1 |r| Show InChI InChI=1S/C18H19ClN6O/c1-10-7-11(3-4-13(10)19)14(8-21-2)25-18-16-15(23-9-24-18)12(17(20)26)5-6-22-16/h3-7,9,14,21H,8H2,1-2H3,(H2,20,26)(H,23,24,25)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369753 (US10233160, Compound 44 | US9981925, Compound 44) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(C)c1 |r| Show InChI InChI=1S/C18H19ClN6O/c1-10-7-11(3-4-13(10)19)14(8-21-2)25-18-16-15(23-9-24-18)12(17(20)26)5-6-22-16/h3-7,9,14,21H,8H2,1-2H3,(H2,20,26)(H,23,24,25)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				Bioorg Med Chem Lett 18: 4181-5 (2008) BindingDB Entry DOI: 10.7270/Q2319Z6K
					More data for this Ligand-Target Pair