Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM369768'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369768 (US10233160, Compound 59 | US9981925, Compound 59) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(c(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C20H18F6N6O/c1-2-28-8-14(10-3-4-12(19(21,22)23)13(7-10)20(24,25)26)32-18-16-15(30-9-31-18)11(17(27)33)5-6-29-16/h3-7,9,14,28H,2,8H2,1H3,(H2,27,33)(H,30,31,32)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369768 (US10233160, Compound 59 | US9981925, Compound 59) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(c(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C20H18F6N6O/c1-2-28-8-14(10-3-4-12(19(21,22)23)13(7-10)20(24,25)26)32-18-16-15(30-9-31-18)11(17(27)33)5-6-29-16/h3-7,9,14,28H,2,8H2,1H3,(H2,27,33)(H,30,31,32)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				Bioorg Med Chem Lett 18: 4181-5 (2008) BindingDB Entry DOI: 10.7270/Q2319Z6K
					More data for this Ligand-Target Pair