Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM369778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369778 (US10233160, Compound 69 | US9981925, Compound 69) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CC(F)C3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H17ClF4N6O/c21-14-2-1-10(5-13(14)20(23,24)25)15(8-31-6-11(22)7-31)30-19-17-16(28-9-29-19)12(18(26)32)3-4-27-17/h1-5,9,11,15H,6-8H2,(H2,26,32)(H,28,29,30)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM369778 (US10233160, Compound 69 | US9981925, Compound 69) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CC(F)C3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H17ClF4N6O/c21-14-2-1-10(5-13(14)20(23,24)25)15(8-31-6-11(22)7-31)30-19-17-16(28-9-29-19)12(18(26)32)3-4-27-17/h1-5,9,11,15H,6-8H2,(H2,26,32)(H,28,29,30)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62.5	n/a	n/a	n/a	n/a	n/a	n/a
Anadys Pharmaceuticals					Assay Description In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...				Bioorg Med Chem Lett 18: 4181-5 (2008) BindingDB Entry DOI: 10.7270/Q2319Z6K
					More data for this Ligand-Target Pair