Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50243775'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243775 (CHEMBL454859 | N,N-dimethyl-1-(6-phenyl-7-(4-((4-(...) Show SMILES CN(C)C1CCN(CC1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 Show InChI InChI=1S/C39H42N10/c1-47(2)32-17-22-49(23-18-32)39-41-25-31-24-33(28-8-4-3-5-9-28)35(42-36(31)44-39)29-13-11-27(12-14-29)26-48-20-15-30(16-21-48)37-43-38(46-45-37)34-10-6-7-19-40-34/h3-14,19,24-25,30,32H,15-18,20-23,26H2,1-2H3,(H,43,45,46)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation by HTRF assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243775 (CHEMBL454859 | N,N-dimethyl-1-(6-phenyl-7-(4-((4-(...) Show SMILES CN(C)C1CCN(CC1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 Show InChI InChI=1S/C39H42N10/c1-47(2)32-17-22-49(23-18-32)39-41-25-31-24-33(28-8-4-3-5-9-28)35(42-36(31)44-39)29-13-11-27(12-14-29)26-48-20-15-30(16-21-48)37-43-38(46-45-37)34-10-6-7-19-40-34/h3-14,19,24-25,30,32H,15-18,20-23,26H2,1-2H3,(H,43,45,46)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation in human by C33a cells by IPKA assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair