Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50312941 ((S)-N1-(5-(isoquinolin-6-yl)-1,3,4-oxadiazol-2-yl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISA | Bioorg Med Chem Lett 20: 1559-64 (2010) Article DOI: 10.1016/j.bmcl.2010.01.067 BindingDB Entry DOI: 10.7270/Q20C4VWX | |||||||||||
More data for this Ligand-Target Pair |