Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50384861'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50384861 (CHEMBL2035019) Show SMILES NC1(CCC1)c1ccc(cc1)-c1nn2ccnc2cc1-c1ccccc1 Show InChI InChI=1S/C22H20N4/c23-22(11-4-12-22)18-9-7-17(8-10-18)21-19(16-5-2-1-3-6-16)15-20-24-13-14-26(20)25-21/h1-3,5-10,13-15H,4,11-12,23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	246	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...				US Patent US8987273 (2015) BindingDB Entry DOI: 10.7270/Q2CZ35WJ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50384861 (CHEMBL2035019) Show SMILES NC1(CCC1)c1ccc(cc1)-c1nn2ccnc2cc1-c1ccccc1 Show InChI InChI=1S/C22H20N4/c23-22(11-4-12-22)18-9-7-17(8-10-18)21-19(16-5-2-1-3-6-16)15-20-24-13-14-26(20)25-21/h1-3,5-10,13-15H,4,11-12,23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	528	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of AKT1				J Med Chem 55: 1261-73 (2012) Article DOI: 10.1021/jm201394e BindingDB Entry DOI: 10.7270/Q2H41SGT
					More data for this Ligand-Target Pair