Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50449753'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50449753 (CHEMBL4170467) Show SMILES Fc1ccc2nc(NC(=O)CSc3nnc(COc4ccc5CCCCc5c4)o3)sc2c1 Show InChI InChI=1S/C22H19FN4O3S2/c23-15-6-8-17-18(10-15)32-21(24-17)25-19(28)12-31-22-27-26-20(30-22)11-29-16-7-5-13-3-1-2-4-14(13)9-16/h5-10H,1-4,11-12H2,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anadolu University Curated by ChEMBL					Assay Description Inhibition of Akt in human A549 cells after 24 hrs by ELISA				Eur J Med Chem 155: 905-924 (2018) Article DOI: 10.1016/j.ejmech.2018.06.049 BindingDB Entry DOI: 10.7270/Q2RX9FN2
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Rattus norvegicus)	BDBM50449753 (CHEMBL4170467) Show SMILES Fc1ccc2nc(NC(=O)CSc3nnc(COc4ccc5CCCCc5c4)o3)sc2c1 Show InChI InChI=1S/C22H19FN4O3S2/c23-15-6-8-17-18(10-15)32-21(24-17)25-19(28)12-31-22-27-26-20(30-22)11-29-16-7-5-13-3-1-2-4-14(13)9-16/h5-10H,1-4,11-12H2,(H,24,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anadolu University Curated by ChEMBL					Assay Description Inhibition of Akt in rat C6 cells after 24 hrs by ELISA				Eur J Med Chem 155: 905-924 (2018) Article DOI: 10.1016/j.ejmech.2018.06.049 BindingDB Entry DOI: 10.7270/Q2RX9FN2
					More data for this Ligand-Target Pair