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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50536178'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50536178
PNG
(CHEMBL4528363)
Show SMILES CC(C)(N)c1ccc(cc1)-n1c(nc2ccc(nc12)-c1ccccc1)-c1cccnc1N
Show InChI InChI=1S/C26H24N6/c1-26(2,28)18-10-12-19(13-11-18)32-24(20-9-6-16-29-23(20)27)31-22-15-14-21(30-25(22)32)17-7-4-3-5-8-17/h3-16H,28H2,1-2H3,(H2,27,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.40n/an/an/an/an/an/a



ArQule Inc.

Curated by ChEMBL


Assay Description
Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...

J Med Chem 59: 6455-69 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00619
BindingDB Entry DOI: 10.7270/Q2RN3CCM
More data for this
Ligand-Target Pair