Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]' and Ligand = 'BDBM16795'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16795 (3-[(2S)-2-amino-3-phenylpropoxy]-5-[3-(furan-2-yl)...) Show SMILES N[C@H](COc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1ccco1)Cc1ccccc1 |r| Show InChI InChI=1S/C24H21N5O2/c25-18(9-16-5-2-1-3-6-16)15-31-19-10-17(12-26-13-19)21-11-20-22(14-27-21)28-29-24(20)23-7-4-8-30-23/h1-8,10-14,18H,9,15,25H2,(H,28,29)/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem 15: 2441-52 (2007) Article DOI: 10.1016/j.bmc.2007.01.010 BindingDB Entry DOI: 10.7270/Q26Q1VGQ
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