Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]' and Ligand = 'BDBM16796'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16796 (3-[(2S)-2-amino-3-phenylpropoxy]-5-[3-(1-methyl-1H...) Show SMILES Cn1cccc1-c1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r| Show InChI InChI=1S/C25H24N6O/c1-31-9-5-8-24(31)25-21-12-22(28-15-23(21)29-30-25)18-11-20(14-27-13-18)32-16-19(26)10-17-6-3-2-4-7-17/h2-9,11-15,19H,10,16,26H2,1H3,(H,29,30)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem 15: 2441-52 (2007) Article DOI: 10.1016/j.bmc.2007.01.010 BindingDB Entry DOI: 10.7270/Q26Q1VGQ
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